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Limited Evidence for a Relationship between HIV-1 Glycan Shield Features in Early Infection and the Development of Neutralization Breadth

Identifying whether viral features present in acute HIV-1 infection predetermine the development of neutralization breadth is critical to vaccine design. Incorporating such features in vaccine antigens could initiate cross-reactive antibody responses that could sufficiently protect vaccinees from HI...

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Detalles Bibliográficos
Autores principales: Li, Yifan, Bai, Hongjun, Sanders-Buell, Eric, Dussupt, Vincent, Townsley, Samantha, Donofrio, Gina, Bose, Meera, O’Sullivan, Anne Marie, Kibuuka, Hannah, Maganga, Lucas, Nitayaphan, Sorachai, Kosgei, Josphat, Pitisuttithum, Punnee, Rerks-Ngarm, Supachai, Eller, Leigh Anne, Michael, Nelson L., Robb, Merlin L., Ake, Julie, Vasan, Sandhya, Tovanabutra, Sodsai, Krebs, Shelly J., Rolland, Morgane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354232/
https://www.ncbi.nlm.nih.gov/pubmed/34160251
http://dx.doi.org/10.1128/JVI.00797-21