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HIV-1 Nef Induces Hck/Lyn-Dependent Expansion of Myeloid-Derived Suppressor Cells Associated with Elevated Interleukin-17/G-CSF Levels

Human immunodeficiency virus (HIV) or simian immunodeficiency virus (SIV) infection causes myelodysplasia, anemia, and accumulation of inflammatory monocytes (CD14(+) CD16(+)) through largely unknown cellular and molecular pathways. The mouse cells thought to be equivalent to human CD14(+) CD16(+) c...

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Detalles Bibliográficos
Autores principales: Priceputu, Elena, Cool, Marc, Bouchard, Nathalie, Caceres-Cortes, Julio Roberto, Lowell, Clifford A., Hanna, Zaher, Jolicoeur, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354241/
https://www.ncbi.nlm.nih.gov/pubmed/34106001
http://dx.doi.org/10.1128/JVI.00471-21