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Interference with the expression of S1PR1 or STAT3 attenuates valvular damage due to rheumatic heart disease

Rheumatic heart disease (RHD) affects numerous individuals annually; however, its pathogenesis remains unclear. The sphingosine 1-phosphate receptor 1 (S1PR1) and signal transducer and activator of transcription 3 (STAT3) have recently been shown to be involved in valvular damage via the promotion o...

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Detalles Bibliográficos
Autores principales: Xian, Shenglin, Chen, Ang, Wu, Yunjiao, Wen, Hong, Lu, Chuanghong, Huang, Feng, Zeng, Zhiyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354313/
https://www.ncbi.nlm.nih.gov/pubmed/34296288
http://dx.doi.org/10.3892/ijmm.2021.5012