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Interference with the expression of S1PR1 or STAT3 attenuates valvular damage due to rheumatic heart disease
Rheumatic heart disease (RHD) affects numerous individuals annually; however, its pathogenesis remains unclear. The sphingosine 1-phosphate receptor 1 (S1PR1) and signal transducer and activator of transcription 3 (STAT3) have recently been shown to be involved in valvular damage via the promotion o...
Autores principales: | Xian, Shenglin, Chen, Ang, Wu, Yunjiao, Wen, Hong, Lu, Chuanghong, Huang, Feng, Zeng, Zhiyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354313/ https://www.ncbi.nlm.nih.gov/pubmed/34296288 http://dx.doi.org/10.3892/ijmm.2021.5012 |
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