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Selenium attenuates ischemia/reperfusion injury-induced damage to the blood-brain barrier in hyperglycemia through PI3K/AKT/mTOR pathway-mediated autophagy inhibition

Ischemic stroke is a leading cause of mortality and disability. Diabetes mellitus, characterized by hyperglycemia, is a common concomitant disease of ischemic stroke, which is associated with autophagy dysfunction and blood-brain barrier (BBB) damage following cerebral ischemia/reperfusion (I/R) inj...

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Detalles Bibliográficos
Autores principales: Yang, Biao, Li, Yaqiong, Ma, Yanmei, Zhang, Xiaopeng, Yang, Lan, Shen, Xilin, Zhang, Jianzhong, Jing, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354314/
https://www.ncbi.nlm.nih.gov/pubmed/34296284
http://dx.doi.org/10.3892/ijmm.2021.5011