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Detrimental role of IL-33/ST2 pathway sustaining a chronic eosinophil-dependent Th2 inflammatory response, tissue damage and parasite burden during Toxocara canis infection in mice

Toxocariasis is a neglected disease that affects people around the world. Humans become infected by accidental ingestion of eggs containing Toxocara canis infective larvae, which upon reaching the intestine, hatch, penetrate the mucosa and migrate to various tissues such as liver, lungs and brain. S...

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Detalles Bibliográficos
Autores principales: Leal-Silva, Thaís, Vieira-Santos, Flaviane, Oliveira, Fabrício Marcus Silva, Padrão, Luiza de Lima Silva, Kraemer, Lucas, da Paixão Matias, Pablo Hemanoel, de Almeida Lopes, Camila, Loiola Ruas, Ana Cristina, de Azevedo, Isabella Carvalho, Nogueira, Denise Silva, Rachid, Milene Alvarenga, Caliari, Marcelo Vidigal, Castro Russo, Remo, Fujiwara, Ricardo Toshio, Bueno, Lilian Lacerda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354467/
https://www.ncbi.nlm.nih.gov/pubmed/34324507
http://dx.doi.org/10.1371/journal.pntd.0009639