Insights into substrate recognition and specificity for IgG by Endoglycosidase S2

Antibodies bind foreign antigens with high affinity and specificity leading to their neutralization and/or clearance by the immune system. The conserved N-glycan on IgG has significant impact on antibody effector function, with the endoglycosidases of Streptococcus pyogenes deglycosylating the IgG t...

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Detalles Bibliográficos
Autores principales: Aytenfisu, Asaminew H., Deredge, Daniel, Klontz, Erik H., Du, Jonathan, Sundberg, Eric J., MacKerell, Alexander D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354483/
https://www.ncbi.nlm.nih.gov/pubmed/34310592
http://dx.doi.org/10.1371/journal.pcbi.1009103

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354483/
https://www.ncbi.nlm.nih.gov/pubmed/34310592
http://dx.doi.org/10.1371/journal.pcbi.1009103

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