Chondro-Protective Effects of Shikimic Acid on Osteoarthritis via Restoring Impaired Autophagy and Suppressing the MAPK/NF-κB Signaling Pathway

Osteoarthritis (OA) is a major cause of cartilage pain and limited mobility in middle-aged and elderly individuals. The degeneration of cartilage induced by inflammation and cartilage anabolic and catabolic disorder plays a key role in OA. Shikimic acid (SA), a natural ingredient extracted from Illi...

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Detalles Bibliográficos
Autores principales: You, Hongbo, Zhang, Rui, Wang, Lingying, Pan, Qiyong, Mao, Zekai, Huang, Xiaojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354550/
https://www.ncbi.nlm.nih.gov/pubmed/34385915
http://dx.doi.org/10.3389/fphar.2021.634822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354550/
https://www.ncbi.nlm.nih.gov/pubmed/34385915
http://dx.doi.org/10.3389/fphar.2021.634822

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