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Chondro-Protective Effects of Shikimic Acid on Osteoarthritis via Restoring Impaired Autophagy and Suppressing the MAPK/NF-κB Signaling Pathway
Osteoarthritis (OA) is a major cause of cartilage pain and limited mobility in middle-aged and elderly individuals. The degeneration of cartilage induced by inflammation and cartilage anabolic and catabolic disorder plays a key role in OA. Shikimic acid (SA), a natural ingredient extracted from Illi...
Autores principales: | You, Hongbo, Zhang, Rui, Wang, Lingying, Pan, Qiyong, Mao, Zekai, Huang, Xiaojian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354550/ https://www.ncbi.nlm.nih.gov/pubmed/34385915 http://dx.doi.org/10.3389/fphar.2021.634822 |
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