Digital Image Analysis of the Proliferation Markers Ki67 and Phosphohistone H3 in Gastroenteropancreatic Neuroendocrine Neoplasms: Accuracy of Grading Compared With Routine Manual Hot Spot Evaluation of the Ki67 Index

Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are rare epithelial neoplasms. Grading is based on mitotic activity or the percentage of Ki67-positive cells in a hot spot. Routine methods have poor intraobserver and interobserver consistency, and objective measurements are lacking. This s...

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Detalles Bibliográficos
Autores principales: Lea, Dordi, Gudlaugsson, Einar G., Skaland, Ivar, Lillesand, Melinda, Søreide, Kjetil, Søreide, Jon A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354564/
https://www.ncbi.nlm.nih.gov/pubmed/33758143
http://dx.doi.org/10.1097/PAI.0000000000000934

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354564/
https://www.ncbi.nlm.nih.gov/pubmed/33758143
http://dx.doi.org/10.1097/PAI.0000000000000934

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