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MIR106A-5p upregulation suppresses autophagy and accelerates malignant phenotype in nasopharyngeal carcinoma

Dysregulated microRNAs (miRNAs) are involved in carcinoma progression, metastasis, and poor prognosis. We demonstrated that in nasopharyngeal carcinoma (NPC), transactivated MIR106A-5p promotes a malignant phenotype by functioning as a macroautophagy/autophagy suppressor by targeting BTG3 (BTG anti-...

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Detalles Bibliográficos
Autores principales: Zhu, Qingwen, Zhang, Qicheng, Gu, Miao, Zhang, Kaiwen, Xia, Tian, Zhang, Siyu, Chen, Wenhui, Yin, Haimeng, Yao, Hui, Fan, Yue, Pan, Si, Xie, Haijing, Liu, Huiting, Cheng, Tianyi, Zhang, Panpan, Zhang, Ting, You, Bo, You, Yiwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354606/
https://www.ncbi.nlm.nih.gov/pubmed/32627648
http://dx.doi.org/10.1080/15548627.2020.1781368