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Processing of the ribosomal ubiquitin-like fusion protein FUBI-eS30/FAU is required for 40S maturation and depends on USP36

In humans and other holozoan organisms, the ribosomal protein eS30 is synthesized as a fusion protein with the ubiquitin-like protein FUBI. However, FUBI is not part of the mature 40S ribosomal subunit and cleaved off by an as-of-yet unidentified protease. How FUBI-eS30 processing is coordinated wit...

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Detalles Bibliográficos
Autores principales: van den Heuvel, Jasmin, Ashiono, Caroline, Gillet, Ludovic C, Dörner, Kerstin, Wyler, Emanuel, Zemp, Ivo, Kutay, Ulrike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354635/
https://www.ncbi.nlm.nih.gov/pubmed/34318747
http://dx.doi.org/10.7554/eLife.70560