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The evolution of hematopoietic cells under cancer therapy

Chemotherapies may increase mutagenesis of healthy cells and change the selective pressures in tissues, thus influencing their evolution. However, their contributions to the mutation burden and clonal expansions of healthy somatic tissues are not clear. Here, exploiting the mutational footprint of s...

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Detalles Bibliográficos
Autores principales: Pich, Oriol, Cortes-Bullich, Albert, Muiños, Ferran, Pratcorona, Marta, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355079/
https://www.ncbi.nlm.nih.gov/pubmed/34376657
http://dx.doi.org/10.1038/s41467-021-24858-3