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The evolution of hematopoietic cells under cancer therapy
Chemotherapies may increase mutagenesis of healthy cells and change the selective pressures in tissues, thus influencing their evolution. However, their contributions to the mutation burden and clonal expansions of healthy somatic tissues are not clear. Here, exploiting the mutational footprint of s...
Autores principales: | Pich, Oriol, Cortes-Bullich, Albert, Muiños, Ferran, Pratcorona, Marta, Gonzalez-Perez, Abel, Lopez-Bigas, Nuria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355079/ https://www.ncbi.nlm.nih.gov/pubmed/34376657 http://dx.doi.org/10.1038/s41467-021-24858-3 |
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