Deletion of TLR4 reduces apoptosis and improves histology in a murine kidney transplant model

Acute kidney injury (AKI) after transplantation of human deceased donor kidneys is associated with upregulation of tubular toll like receptor 4 (TLR4), but whether TLR4 is required for AKI is unknown. We hypothesized that TLR4 knockout mice (TLR4KO) subjected to cold ischemia followed by kidney tran...

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Detalles Bibliográficos
Autores principales: Jain, Swati, Plenter, Robert, Nydam, Trevor, Gill, Ronald G., Jani, Alkesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355104/
https://www.ncbi.nlm.nih.gov/pubmed/34376755
http://dx.doi.org/10.1038/s41598-021-95504-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355104/
https://www.ncbi.nlm.nih.gov/pubmed/34376755
http://dx.doi.org/10.1038/s41598-021-95504-7

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