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Deletion of TLR4 reduces apoptosis and improves histology in a murine kidney transplant model
Acute kidney injury (AKI) after transplantation of human deceased donor kidneys is associated with upregulation of tubular toll like receptor 4 (TLR4), but whether TLR4 is required for AKI is unknown. We hypothesized that TLR4 knockout mice (TLR4KO) subjected to cold ischemia followed by kidney tran...
Autores principales: | Jain, Swati, Plenter, Robert, Nydam, Trevor, Gill, Ronald G., Jani, Alkesh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355104/ https://www.ncbi.nlm.nih.gov/pubmed/34376755 http://dx.doi.org/10.1038/s41598-021-95504-7 |
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