A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration

Myocardial regeneration is restricted to early postnatal life, when mammalian cardiomyocytes still retain the ability to proliferate. The molecular cues that induce cell cycle arrest of neonatal cardiomyocytes towards terminally differentiated adult heart muscle cells remain obscure. Here we report...

Descripción completa

Detalles Bibliográficos
Autores principales: Raso, Andrea, Dirkx, Ellen, Sampaio-Pinto, Vasco, el Azzouzi, Hamid, Cubero, Ryan J., Sorensen, Daniel W., Ottaviani, Lara, Olieslagers, Servé, Huibers, Manon M., de Weger, Roel, Siddiqi, Sailay, Moimas, Silvia, Torrini, Consuelo, Zentillin, Lorena, Braga, Luca, Nascimento, Diana S., da Costa Martins, Paula A., van Berlo, Jop H., Zacchigna, Serena, Giacca, Mauro, De Windt, Leon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355162/
https://www.ncbi.nlm.nih.gov/pubmed/34376683
http://dx.doi.org/10.1038/s41467-021-25211-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355162/
https://www.ncbi.nlm.nih.gov/pubmed/34376683
http://dx.doi.org/10.1038/s41467-021-25211-4

Ejemplares similares