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A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration
Myocardial regeneration is restricted to early postnatal life, when mammalian cardiomyocytes still retain the ability to proliferate. The molecular cues that induce cell cycle arrest of neonatal cardiomyocytes towards terminally differentiated adult heart muscle cells remain obscure. Here we report...
Autores principales: | Raso, Andrea, Dirkx, Ellen, Sampaio-Pinto, Vasco, el Azzouzi, Hamid, Cubero, Ryan J., Sorensen, Daniel W., Ottaviani, Lara, Olieslagers, Servé, Huibers, Manon M., de Weger, Roel, Siddiqi, Sailay, Moimas, Silvia, Torrini, Consuelo, Zentillin, Lorena, Braga, Luca, Nascimento, Diana S., da Costa Martins, Paula A., van Berlo, Jop H., Zacchigna, Serena, Giacca, Mauro, De Windt, Leon J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355162/ https://www.ncbi.nlm.nih.gov/pubmed/34376683 http://dx.doi.org/10.1038/s41467-021-25211-4 |
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