Chemogenetic inhibition of prefrontal projection neurons constrain top-down control of attention in young but not aged rats

The prefrontal cortex (PFC) governs top-down control of attention and is known to be vulnerable in aging. Cortical reorganization with increased PFC recruitment is suggested to account for functional compensation. Here, we hypothesized that reduced PFC output would exert differential effects on atte...

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Detalles Bibliográficos
Autores principales: Duggan, Michael R., Joshi, Surbhi, Strupp, Jacob, Parikh, Vinay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355172/
https://www.ncbi.nlm.nih.gov/pubmed/34247267
http://dx.doi.org/10.1007/s00429-021-02336-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355172/
https://www.ncbi.nlm.nih.gov/pubmed/34247267
http://dx.doi.org/10.1007/s00429-021-02336-2

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