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Chemogenetic inhibition of prefrontal projection neurons constrain top-down control of attention in young but not aged rats
The prefrontal cortex (PFC) governs top-down control of attention and is known to be vulnerable in aging. Cortical reorganization with increased PFC recruitment is suggested to account for functional compensation. Here, we hypothesized that reduced PFC output would exert differential effects on atte...
Autores principales: | Duggan, Michael R., Joshi, Surbhi, Strupp, Jacob, Parikh, Vinay |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355172/ https://www.ncbi.nlm.nih.gov/pubmed/34247267 http://dx.doi.org/10.1007/s00429-021-02336-2 |
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