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The molecular basis, genetic control and pleiotropic effects of local gene co-expression

Nearby genes are often expressed as a group. Yet, the prevalence, molecular mechanisms and genetic control of local gene co-expression are far from being understood. Here, by leveraging gene expression measurements across 49 human tissues and hundreds of individuals, we find that local gene co-expre...

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Detalles Bibliográficos
Autores principales: Ribeiro, Diogo M., Rubinacci, Simone, Ramisch, Anna, Hofmeister, Robin J., Dermitzakis, Emmanouil T., Delaneau, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355184/
https://www.ncbi.nlm.nih.gov/pubmed/34376650
http://dx.doi.org/10.1038/s41467-021-25129-x