Chemoprophylaxis vaccination with a Plasmodium liver stage autophagy mutant affords enhanced and long-lasting protection

Genetically attenuated sporozoite vaccines can elicit long-lasting protection against malaria but pose risks of breakthrough infection. Chemoprophylaxis vaccination (CVac) has proven to be the most effective vaccine strategy against malaria. Here, we demonstrate that a liver stage-specific autophagy...

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Detalles Bibliográficos
Autores principales: Sahu, Tejram, Gehrke, Ella J., Flores-Garcia, Yevel, Mlambo, Godfree, Romano, Julia D., Coppens, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355287/
https://www.ncbi.nlm.nih.gov/pubmed/34376691
http://dx.doi.org/10.1038/s41541-021-00360-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355287/
https://www.ncbi.nlm.nih.gov/pubmed/34376691
http://dx.doi.org/10.1038/s41541-021-00360-1

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