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CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for Plasmodium falciparum malaria transmission research

The malaria parasite Plasmodium falciparum replicates inside erythrocytes in the blood of infected humans. During each replication cycle, a small proportion of parasites commits to sexual development and differentiates into gametocytes, which are essential for parasite transmission via the mosquito...

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Detalles Bibliográficos
Autores principales: Boltryk, Sylwia D., Passecker, Armin, Alder, Arne, Carrington, Eilidh, van de Vegte-Bolmer, Marga, van Gemert, Geert-Jan, van der Starre, Alex, Beck, Hans-Peter, Sauerwein, Robert W., Kooij, Taco W. A., Brancucci, Nicolas M. B., Proellochs, Nicholas I., Gilberger, Tim-Wolf, Voss, Till S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355313/
https://www.ncbi.nlm.nih.gov/pubmed/34376675
http://dx.doi.org/10.1038/s41467-021-24954-4