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CRISPR/Cas9-engineered inducible gametocyte producer lines as a valuable tool for Plasmodium falciparum malaria transmission research
The malaria parasite Plasmodium falciparum replicates inside erythrocytes in the blood of infected humans. During each replication cycle, a small proportion of parasites commits to sexual development and differentiates into gametocytes, which are essential for parasite transmission via the mosquito...
Autores principales: | Boltryk, Sylwia D., Passecker, Armin, Alder, Arne, Carrington, Eilidh, van de Vegte-Bolmer, Marga, van Gemert, Geert-Jan, van der Starre, Alex, Beck, Hans-Peter, Sauerwein, Robert W., Kooij, Taco W. A., Brancucci, Nicolas M. B., Proellochs, Nicholas I., Gilberger, Tim-Wolf, Voss, Till S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355313/ https://www.ncbi.nlm.nih.gov/pubmed/34376675 http://dx.doi.org/10.1038/s41467-021-24954-4 |
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