The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice light sheet microscopy

Macropinosomes are formed by shaping actin-rich plasma membrane ruffles into large intracellular organelles in a phosphatidylinositol 3-kinase (PI3K)-coordinated manner. Here, we utilize lattice lightsheet microscopy and image visualization methods to map the three-dimensional structure and dynamics...

Descripción completa

Detalles Bibliográficos
Autores principales: Quinn, Shayne E., Huang, Lu, Kerkvliet, Jason G., Swanson, Joel A., Smith, Steve, Hoppe, Adam D., Anderson, Robert B., Thiex, Natalie W., Scott, Brandon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355319/
https://www.ncbi.nlm.nih.gov/pubmed/34376698
http://dx.doi.org/10.1038/s41467-021-25187-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355319/
https://www.ncbi.nlm.nih.gov/pubmed/34376698
http://dx.doi.org/10.1038/s41467-021-25187-1

Ejemplares similares