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Nanopore sequencing of brain-derived full-length circRNAs reveals circRNA-specific exon usage, intron retention and microexons

Circular RNA (circRNA) is a class of covalently joined non-coding RNAs with functional roles in a wide variety of cellular processes. Their composition shows extensive overlap with exons found in linear mRNAs making it difficult to delineate their composition using short-read RNA sequencing, particu...

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Detalles Bibliográficos
Autores principales: Rahimi, Karim, Venø, Morten T., Dupont, Daniel M., Kjems, Jørgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355340/
https://www.ncbi.nlm.nih.gov/pubmed/34376658
http://dx.doi.org/10.1038/s41467-021-24975-z