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Common genetic variants with fetal effects on birth weight are enriched for proximity to genes implicated in rare developmental disorders

Birth weight is an important factor in newborn survival; both low and high birth weights are associated with adverse later-life health outcomes. Genome-wide association studies (GWAS) have identified 190 loci associated with maternal or fetal effects on birth weight. Knowledge of the underlying caus...

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Detalles Bibliográficos
Autores principales: Beaumont, Robin N, Mayne, Isabelle K, Freathy, Rachel M, Wright, Caroline F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355446/
https://www.ncbi.nlm.nih.gov/pubmed/33682876
http://dx.doi.org/10.1093/hmg/ddab060