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Hypomethylation of Rnase6 Promoter Enhances Proliferation and Migration of Murine Aortic Vascular Smooth Muscle Cells and Aggravates Atherosclerosis in Mice

Background: Accumulating evidence has implicated DNA methylation in the progression of atherosclerosis (AS). Rnase6 has been reported to be upregulated in AS development, but the specific regulatory mechanism remains unclear. Material/Methods: Peripheral blood and sclerotic plaque tissues from 25 AS...

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Detalles Bibliográficos
Autores principales: Fang, YongPeng, Li, JinShuang, Niu, XuDong, Ma, NingShun, Zhao, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355590/
https://www.ncbi.nlm.nih.gov/pubmed/34395402
http://dx.doi.org/10.3389/fbioe.2021.695461