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Klotho and calciprotein particles as therapeutic targets against accelerated ageing

The klotho gene, named after a Greek goddess who spins the thread of life, was identified as a putative ‘ageing-suppressor’ gene. Klotho-deficient mice exhibit complex ageing-like phenotypes including hypogonadism, arteriosclerosis (vascular calcification), cardiac hypertrophy, osteopenia, sarcopeni...

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Detalles Bibliográficos
Autor principal: Kuro-o, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355631/
https://www.ncbi.nlm.nih.gov/pubmed/34374422
http://dx.doi.org/10.1042/CS20201453