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MicroRNA-18a-5p regulates the Warburg effect by targeting hypoxia-inducible factor 1α in the K562/ADM cell line

The Warburg effect is involved in drug resistance and recurrence of cancer, and poses a challenge for the treatment of chronic myelogenous leukemia (CML). Hypoxia-inducible factor 1α (HIF-1α) plays a key role in the Warburg effect. microRNAs (miRs) targeting HIF-1α have potential of regulating such...

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Detalles Bibliográficos
Autores principales: Wu, Kun, Guo, Chong, Li, Yixun, Yang, Jinrong, Zhou, Qiang, Cheng, Shenju, Li, Yanhong, Nie, Bo, Zeng, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355681/
https://www.ncbi.nlm.nih.gov/pubmed/34447462
http://dx.doi.org/10.3892/etm.2021.10503