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Herbal melanin induces interleukin-1β secretion and production by human THP-1 monocytes via Toll-like receptor 2 and p38 MAPK activation

Herbal melanin (HM), extracted from Nigella sativa, is known for its immunogenic properties through the modulation of cytokine production via Toll-like receptor (TLR)4. TLRs play a crucial role in the host defense through the regulation of innate and adaptive immune responses. However, the potential...

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Detalles Bibliográficos
Autores principales: El-Obeid, Adila, Yahya, Wesam Bin, Almuzzaini, Bader, Tuwaijri, Abeer Al, Najdi, Maria, Hassib, Adil, Matou-Nasri, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355711/
https://www.ncbi.nlm.nih.gov/pubmed/34447474
http://dx.doi.org/10.3892/etm.2021.10515