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Benazepril hydrochloride protects against doxorubicin cardiotoxicity by regulating the PI3K/Akt pathway

Doxorubicin (DOX) stimulates the generation of reactive oxygen species, thereby impairing mitochondrial functions. Angiotensin-converting enzyme inhibitors (ACEIs) have been identified to exhibit protective effects on cardiovascular diseases. The present study aimed to test the hypothesis that an AC...

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Detalles Bibliográficos
Autores principales: Zhan, Lan, Wang, Xiangxiu, Zhang, Yanjing, Zhu, Guonian, Ding, Yu, Chen, Xuemei, Jiang, Wei, Wu, Sisi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355712/
https://www.ncbi.nlm.nih.gov/pubmed/34447475
http://dx.doi.org/10.3892/etm.2021.10516