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Benazepril hydrochloride protects against doxorubicin cardiotoxicity by regulating the PI3K/Akt pathway
Doxorubicin (DOX) stimulates the generation of reactive oxygen species, thereby impairing mitochondrial functions. Angiotensin-converting enzyme inhibitors (ACEIs) have been identified to exhibit protective effects on cardiovascular diseases. The present study aimed to test the hypothesis that an AC...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355712/ https://www.ncbi.nlm.nih.gov/pubmed/34447475 http://dx.doi.org/10.3892/etm.2021.10516 |