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Engineering a new vaccine platform for heterologous antigen delivery in live-attenuated Mycobacterium tuberculosis

Live vaccines are attractive vehicles for antigen delivery as a strategy to immunize against heterologous pathogens. The live vaccine MTBVAC is based on rational attenuation of Mycobacterium tuberculosis with the objective of improving BCG protection against pulmonary tuberculosis. However, the deve...

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Detalles Bibliográficos
Autores principales: Broset, Esther, Calvet Seral, Juan, Arnal, Carmen, Uranga, Santiago, Kanno, Alex I., Leite, Luciana C.C., Martín, Carlos, Gonzalo-Asensio, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355830/
https://www.ncbi.nlm.nih.gov/pubmed/34429847
http://dx.doi.org/10.1016/j.csbj.2021.07.035