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Acute toxicity evaluation of a novel ceramide analog for the treatment of breast cancer

We have previously reported that treating triple-negative tumor bearing nude mice with intraperitoneal (ip) 10 mg/kg body weight of (S,E)-3-hydroxy-2-(2-hydroxybenzylidene)amino-N-tetradecylpropanamide, a ceramide analog, 5 days per week for 3 weeks, was shown not only to suppress tumor growth but a...

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Detalles Bibliográficos
Autores principales: Ponnapakkam, Tulasi, Bongay-Williams, Kyla, Beamon, Teresa, Hooks, Royce, Cheatham, Degrick, Goyal, Navneet, Anbalagan, Muralidharan, Foroozesh, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355835/
https://www.ncbi.nlm.nih.gov/pubmed/34401362
http://dx.doi.org/10.1016/j.toxrep.2021.07.022