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Epigenetic rewiring of skeletal muscle enhancers after exercise training supports a role in whole-body function and human health

OBJECTIVES: Regular physical exercise improves health by reducing the risk of a plethora of chronic disorders. We hypothesized that endurance exercise training remodels the activity of gene enhancers in skeletal muscle and that this remodeling contributes to the beneficial effects of exercise on hum...

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Detalles Bibliográficos
Autores principales: Williams, Kristine, Carrasquilla, Germán D., Ingerslev, Lars Roed, Hochreuter, Mette Yde, Hansson, Svenja, Pillon, Nicolas J., Donkin, Ida, Versteyhe, Soetkin, Zierath, Juleen R., Kilpeläinen, Tuomas O., Barrès, Romain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355925/
https://www.ncbi.nlm.nih.gov/pubmed/34252634
http://dx.doi.org/10.1016/j.molmet.2021.101290