Investigation of the Role of Neurokinin-1 Receptor Inhibition Using Aprepitant in the Apoptotic Cell Death through PI3K/Akt/NF-κB Signal Transduction Pathways in Colon Cancer Cells

BACKGROUND: Colorectal cancer (CRC) is recognized as one of the most common malignancies with a high mortality rate worldwide, supporting the necessity for an effective novel antitumor drug to improve current therapy's effectiveness. Substance P (SP) is the essential member of the tachykinins (...

Descripción completa

Detalles Bibliográficos
Autores principales: Ghahremanloo, Atefeh, Javid, Hossein, Afshari, Amir R., Hashemy, Seyed Isaac
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355960/
https://www.ncbi.nlm.nih.gov/pubmed/34395609
http://dx.doi.org/10.1155/2021/1383878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355960/
https://www.ncbi.nlm.nih.gov/pubmed/34395609
http://dx.doi.org/10.1155/2021/1383878

Ejemplares similares