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Investigation of the Role of Neurokinin-1 Receptor Inhibition Using Aprepitant in the Apoptotic Cell Death through PI3K/Akt/NF-κB Signal Transduction Pathways in Colon Cancer Cells

BACKGROUND: Colorectal cancer (CRC) is recognized as one of the most common malignancies with a high mortality rate worldwide, supporting the necessity for an effective novel antitumor drug to improve current therapy's effectiveness. Substance P (SP) is the essential member of the tachykinins (...

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Detalles Bibliográficos
Autores principales:	Ghahremanloo, Atefeh, Javid, Hossein, Afshari, Amir R., Hashemy, Seyed Isaac
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355960/ https://www.ncbi.nlm.nih.gov/pubmed/34395609 http://dx.doi.org/10.1155/2021/1383878

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