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HIF-1α-Mediated miR-623 Regulates Apoptosis and Inflammatory Responses of Nucleus Pulposus Induced by Oxidative Stress via Targeting TXNIP

Excessive apoptosis and inflammatory responses of nucleus pulposus (NP) cells induced by oxidative stress contribute to intervertebral disc degeneration (IVDD). Though some microRNAs are associated with IVDD, the specific microRNA that can mediate apoptotic and inflammatory responses of NP cells ind...

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Detalles Bibliográficos
Autores principales: Bao, Xiaogang, Wang, Zhenhua, Jia, Qi, Shen, Sibo, Wu, Likang, Jiang, Qi, Li, Changwei, Xu, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355979/
https://www.ncbi.nlm.nih.gov/pubmed/34394829
http://dx.doi.org/10.1155/2021/6389568