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Adipose Stromal Cell-Secretome Counteracts Profibrotic Signals From IPF Lung Matrices

Introduction: Idiopathic pulmonary fibrosis (IPF) is a fibrotic lung disease characterized by excess deposition and altered structure of extracellular matrix (ECM) in the lungs. The fibrotic ECM is paramount in directing resident cells toward a profibrotic phenotype. Collagens, an important part of...

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Detalles Bibliográficos
Autores principales: Vasse, Gwenda F., Van Os, Lisette, De Jager, Marina, Jonker, Marnix R., Borghuis, Theo, Van Den Toorn, L. Tim, Jellema, Pytrick, White, Eric S., Van Rijn, Patrick, Harmsen, Martin C., Heijink, Irene H., Melgert, Barbro N., Burgess, Janette K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8355988/
https://www.ncbi.nlm.nih.gov/pubmed/34393771
http://dx.doi.org/10.3389/fphar.2021.669037