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Tumor microenvironment evaluation promotes precise checkpoint immunotherapy of advanced gastric cancer

BACKGROUND: Durable efficacy of immune checkpoint blockade (ICB) occurred in a small number of patients with metastatic gastric cancer (mGC) and the determinant biomarker of response to ICB remains unclear. METHODS: We developed an open-source TMEscore R package, to quantify the tumor microenvironme...

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Detalles Bibliográficos
Autores principales: Zeng, Dongqiang, Wu, Jiani, Luo, Huiyan, Li, Yong, Xiao, Jian, Peng, Jianjun, Ye, Zilan, Zhou, Rui, Yu, Yunfang, Wang, Gaofeng, Huang, Na, Wu, Jianhua, Rong, Xiaoxiang, Sun, Li, Sun, Huiying, Qiu, Wenjun, Xue, Yichen, Bin, Jianping, Liao, Yulin, Li, Nailin, Shi, Min, Kim, Kyoung-Mee, Liao, Wangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356190/
https://www.ncbi.nlm.nih.gov/pubmed/34376552
http://dx.doi.org/10.1136/jitc-2021-002467