Using single-nucleus RNA-sequencing to interrogate transcriptomic profiles of archived human pancreatic islets

BACKGROUND: Human pancreatic islets are a central focus of research in metabolic studies. Transcriptomics is frequently used to interrogate alterations in cultured human islet cells using single-cell RNA-sequencing (scRNA-seq). We introduce single-nucleus RNA-sequencing (snRNA-seq) as an alternative...

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Detalles Bibliográficos
Autores principales: Basile, Giorgio, Kahraman, Sevim, Dirice, Ercument, Pan, Hui, Dreyfuss, Jonathan M., Kulkarni, Rohit N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356387/
https://www.ncbi.nlm.nih.gov/pubmed/34376240
http://dx.doi.org/10.1186/s13073-021-00941-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356387/
https://www.ncbi.nlm.nih.gov/pubmed/34376240
http://dx.doi.org/10.1186/s13073-021-00941-8

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