Microglial inclusions and neurofilament light chain release follow neuronal α-synuclein lesions in long-term brain slice cultures

BACKGROUND: Proteopathic brain lesions are a hallmark of many age-related neurodegenerative diseases including synucleinopathies and develop at least a decade before the onset of clinical symptoms. Thus, understanding of the initiation and propagation of such lesions is key for developing therapeuti...

Descripción completa

Detalles Bibliográficos
Autores principales: Barth, Melanie, Bacioglu, Mehtap, Schwarz, Niklas, Novotny, Renata, Brandes, Janine, Welzer, Marc, Mazzitelli, Sonia, Häsler, Lisa M., Schweighauser, Manuel, Wuttke, Thomas V., Kronenberg-Versteeg, Deborah, Fog, Karina, Ambjørn, Malene, Alik, Ania, Melki, Ronald, Kahle, Philipp J., Shimshek, Derya R., Koch, Henner, Jucker, Mathias, Tanriöver, Gaye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356412/
https://www.ncbi.nlm.nih.gov/pubmed/34380535
http://dx.doi.org/10.1186/s13024-021-00471-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356412/
https://www.ncbi.nlm.nih.gov/pubmed/34380535
http://dx.doi.org/10.1186/s13024-021-00471-2

Ejemplares similares