GraphDTI: A robust deep learning predictor of drug-target interactions from multiple heterogeneous data

Traditional techniques to identify macromolecular targets for drugs utilize solely the information on a query drug and a putative target. Nonetheless, the mechanisms of action of many drugs depend not only on their binding affinity toward a single protein, but also on the signal transduction through...

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Detalles Bibliográficos
Autores principales: Liu, Guannan, Singha, Manali, Pu, Limeng, Neupane, Prasanga, Feinstein, Joseph, Wu, Hsiao-Chun, Ramanujam, J., Brylinski, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356453/
https://www.ncbi.nlm.nih.gov/pubmed/34380569
http://dx.doi.org/10.1186/s13321-021-00540-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356453/
https://www.ncbi.nlm.nih.gov/pubmed/34380569
http://dx.doi.org/10.1186/s13321-021-00540-0

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