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Mesenchymal stem cell-derived exosomal miR-146a reverses diabetic β-cell dedifferentiation

BACKGROUND: Mesenchymal stem cells (MSCs) show promising therapeutic potential in treating type 2 diabetes mellitus (T2DM) in clinical studies. Accumulating evidence has suggested that the therapeutic effects of MSCs are not due to their direct differentiation into functional β-cells but are instead...

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Detalles Bibliográficos
Autores principales: He, Qin, Song, Jia, Cui, Chen, Wang, Jinbang, Hu, Huiqing, Guo, Xinghong, Yang, Mengmeng, Wang, Lingshu, Yan, Fei, Liang, Kai, Liu, Zhaojian, Liu, Fuqiang, Sun, Zheng, Dong, Ming, Hou, Xinguo, Chen, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356465/
https://www.ncbi.nlm.nih.gov/pubmed/34380570
http://dx.doi.org/10.1186/s13287-021-02371-0