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N-methyl mesoporphyrin IX as a highly selective light-up probe for G-quadruplex DNA

N-methyl mesoporphyrin IX (NMM) is a water-soluble, non-symmetric porphyrin with excellent optical properties and unparalleled selectivity for G-quadruplex (GQ) DNA. G-quadruplexes are non-canonical DNA structures formed by guanine-rich sequences. They are implicated in genomic stability, longevity,...

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Detalles Bibliográficos
Autores principales: Yett, Ariana, Lin, Linda Yingqi, Beseiso, Dana, Miao, Joanne, Yatsunyk, Liliya A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356643/
https://www.ncbi.nlm.nih.gov/pubmed/34385812
http://dx.doi.org/10.1142/s1088424619300179