Catalytic enantioselective synthesis of benzocyclobutenols and cyclobutanols via a sequential reduction/C–H functionalization

We report here a sequential enantioselective reduction/C–H functionalization to install contiguous stereogenic carbon centers of benzocyclobutenols and cyclobutanols. This strategy features a practical enantioselective reduction of a ketone and a diastereospecific iridium-catalyzed C–H silylation. F...

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Detalles Bibliográficos
Autores principales: Chen, Jun, Shi, Zhan, Li, Chunyu, Lu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356817/
https://www.ncbi.nlm.nih.gov/pubmed/34447553
http://dx.doi.org/10.1039/d1sc02119b

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356817/
https://www.ncbi.nlm.nih.gov/pubmed/34447553
http://dx.doi.org/10.1039/d1sc02119b

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