Adapting decarbonylation chemistry for the development of prodrugs capable of in vivo delivery of carbon monoxide utilizing sweeteners as carrier molecules

Carbon monoxide as an endogenous signaling molecule exhibits pharmacological efficacy in various animal models of organ injury. To address the difficulty in using CO gas as a therapeutic agent for widespread applications, we are interested in developing CO prodrugs through bioreversible caging of CO...

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Detalles Bibliográficos
Autores principales: De La Cruz, Ladie Kimberly, Yang, Xiaoxiao, Menshikh, Anna, Brewer, Maya, Lu, Wen, Wang, Minjia, Wang, Siming, Ji, Xingyue, Cachuela, Alyssa, Yang, Haichun, Gallo, David, Tan, Chalet, Otterbein, Leo, de Caestecker, Mark, Wang, Binghe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356820/
https://www.ncbi.nlm.nih.gov/pubmed/34447558
http://dx.doi.org/10.1039/d1sc02711e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8356820/
https://www.ncbi.nlm.nih.gov/pubmed/34447558
http://dx.doi.org/10.1039/d1sc02711e

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