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Histone demethylase AMX-1 is necessary for proper sensitivity to interstrand crosslink DNA damage
Histone methylation is dynamically regulated to shape the epigenome and adjust central nuclear processes including transcription, cell cycle control and DNA repair. Lysine-specific histone demethylase 2 (LSD2) has been implicated in multiple types of human cancers. However, its functions remain poor...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357103/ https://www.ncbi.nlm.nih.gov/pubmed/34329293 http://dx.doi.org/10.1371/journal.pgen.1009715 |