Cargando…

Histone demethylase AMX-1 is necessary for proper sensitivity to interstrand crosslink DNA damage

Histone methylation is dynamically regulated to shape the epigenome and adjust central nuclear processes including transcription, cell cycle control and DNA repair. Lysine-specific histone demethylase 2 (LSD2) has been implicated in multiple types of human cancers. However, its functions remain poor...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiaojuan, Tian, Sisi, Beese-Sims, Sara E., Chen, Jingjie, Shin, Nara, Colaiácovo, Monica P., Kim, Hyun-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357103/
https://www.ncbi.nlm.nih.gov/pubmed/34329293
http://dx.doi.org/10.1371/journal.pgen.1009715