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RHOX10 drives mouse spermatogonial stem cell establishment through a transcription factor signaling cascade
Spermatogonial stem cells (SSCs) are essential for male fertility. Here, we report that mouse SSC generation is driven by a transcription factor (TF) cascade controlled by the homeobox protein, RHOX10, which acts by driving the differentiation of SSC precursors called pro-spermatogonia (ProSG). We i...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357189/ https://www.ncbi.nlm.nih.gov/pubmed/34289349 http://dx.doi.org/10.1016/j.celrep.2021.109423 |