RHOX10 drives mouse spermatogonial stem cell establishment through a transcription factor signaling cascade

Spermatogonial stem cells (SSCs) are essential for male fertility. Here, we report that mouse SSC generation is driven by a transcription factor (TF) cascade controlled by the homeobox protein, RHOX10, which acts by driving the differentiation of SSC precursors called pro-spermatogonia (ProSG). We i...

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Detalles Bibliográficos
Autores principales: Tan, Kun, Song, Hye-Won, Wilkinson, Miles F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8357189/
https://www.ncbi.nlm.nih.gov/pubmed/34289349
http://dx.doi.org/10.1016/j.celrep.2021.109423

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